Spravato (Esketamine)

Spravato (Esketamine)

Find a new path forward with a treatment designed for more complex or persistent depression.

When is Spravato appropriate?

Treatment ‑resistant cases

When standard antidepressants have not provided sufficient relief after an adequate trial.

Limited progress

When symptoms have persisted for an extended period, often despite ongoing treatment.

Complex presentations

When multiple factors, including co‑occurring conditions, affect your treatment response.

Alternative interventions

When you want to explore advanced, evidence‑based options beyond conventional medication.

A breakthrough therapy for treatment‑resistant depression

At Nu Leaf, Spravato is administered in a safe, structured setting under close medical supervision. Each session is carefully monitored, with support before, during, and after treatment.

This approach is designed for individuals with treatment-resistant depression, providing a new path forward when other options have not been effective.

  • In-clinic nasal spray treatment (Spravato) administered by your provider
  • Continuous monitoring throughout the session for safety and support
  • A dedicated recovery period before you leave the clinic
  • Ongoing guidance to adjust and track your treatment over time

What to prepare

There’s no need to prepare perfectly. If it’s helpful, consider reflecting on when your symptoms began, what has changed over time, and any prior treatments you’ve tried.

  • Bring a list of current medications or supplements
  • Note past diagnoses or treatments, if known
  • Think about what feels most pressing right now
  • Come ready to speak honestly

We’re here whenever you’re ready

Starting care doesn’t require having everything figured out. We’ll help you take 
the next step at a pace that feels right.

A gentler way to begin and continue

At Nu Leaf, we’ve made it our mission to make your mental health care journey easy to start and sustain over time.

Book an appointment

Reach out with an appointment that fits your schedule, in person or virtually, using our self-schedule system.

1

Attend your first session

Connect with your designated mental health practitioner who truly listens and helps you find the support you need.

2

Stay connected

Log in to your patient portal to message your care team or request refills as part of your medication management for mental health.

3
Accepted insurance
About visits and costs
Choose in-person or online mental health treatment, with pricing based on your needs.
Private pay
  • Pay out of pocket for our services without insurance.*
  • 20% off for students with active enrollment at any college
Includes:
Diagnostic assessments
Access to patient portal
Prescription medication
Virtual and/or in-person
Therapy Session
*If you have “out of network” insurance benefits, we can provide you with a “superbill”. Many insurances will reimburse a percentage of your visit costs. Please contact your insurance for details*
For pricing on initial visits and follow-ups
Insurance-based
  • Pricing is subject to your insurance benefits. 

    Please refer to your insurance provider for more details.
  • Medication cost depends on your insurance benefits.
Includes:
Diagnostic assessments
Access to patient portal
Prescription medication
Virtual and/or in-person
Therapy Session**
*If you have “out of network” insurance benefits we can provide you with a “superbill”. Many insurances will reimburse a percentage of your visit costs. Contact your insurance for details* **Number of visits may depends on your needs/provider discretion
Pricing varies by insurance coverage*

Where to go next

NEw patient
If you’re new
We’ll begin by listening carefully and understanding your experience, then help you determine what comes next.
What to expect
A comprehensive evaluation with a nurse practitioner
Time to talk through what you’re experiencing
Guidance on next steps, including treatment options
Returning patient
If you’re already a patient
We’ve designed our approach to stay simple and connected, so support continues between visits and adjusts as your needs change, without starting over.
What to expect
Easy follow-ups via your HIPAA-compliant patient portal
Messaging, scheduling, and medication refills in one place
Care that adapts as your needs change
Frequently asked questions
Spravato is administered as a nasal spray in a clinical setting. Each session is supervised by your care team, with time set aside before, during, and after treatment to monitor how you’re feeling and ensure everything stays safe and controlled.
Experiences can vary, but some patients may feel relaxed, detached, or slightly drowsy during treatment. These effects are temporary and monitored closely. Most patients return to their usual state within a few hours after the session.
Yes. Because of how Spravato can affect awareness and coordination, you’ll need someone to drive you home after each session. This helps ensure your safety as the effects wear off.
Spravato is typically recommended for individuals with treatment-resistant depression or those who haven’t responded to standard medications. Your clinician will review your history and current needs to determine if it’s appropriate for you.
In many cases, yes. Spravato is often used alongside other medications. Your clinician will review your current treatment and make sure everything works safely together.